Bacterial genome annotations are accumulating rapidly in the GenBank database and the use of automated annotation technologies to create these annotations has become the norm.However, these automated methods commonly result in a small, but significant percentage of genome annotation errors.To improve accuracy and reliability, we analyzed the Caulob
BackgroundTumour suppressor genes are often transcriptionally silenced by promoter hypermethylation, and recent research has implicated alterations in chromatin structure as the mechanistic basis for this repression.In addition to DNA methylation, other epigenetic post-translational modifications that modulate the stability and binding of specific
Recently, the development of a methodology for obtaining evidence of clinical efficacy and safety of medical technologies based on the collection and analysis of real clinical practice data (real-world data; RWD; real-world evidence; RWE) has become extremely relevant.Different types of research are used in RWD/RWE.It must develop a unified methodo
BACKGROUND:Whale sharks are a declining species for which little biological data is available.While these animals are protected in many parts of their range, they are fished legally and illegally in some countries.Baseline biological and ecological data are needed to gold ps5 controller skin allow the formulation of an effective conservation plan f